Friday 17 May 2019

Early dengue virus infection could 'defuse' Zika virus

"We now know for sure that Zika virus infection during pregnancy can affect the unborn foetus in such a way that the child develops microcephaly and other severe symptoms," explains Prof Felix Drexler, a virologist at Charité who has been developing diagnostic tests for Zika and other viruses at the DZIF. Just a few years ago, pictures of affected newborns were cause for worldwide dismay and perplexity. "However, what we did not understand then was that high incidence of microcephaly seemed to occur particularly in northeastern Brazil," says Drexler. Why are expecting mothers in these regions at a higher risk of developing a severe Zika-associated disease than in other regions? The scientists consequently began to search for cofactors that have an influence on whether a Zika infection during pregnancy will develop fatal consequences or not.

* This article was originally published here

Clinical trial improves treatment of genetic rickets

A new study shows a drug developed in conjunction with investigators at Indiana University School of Medicine to alleviate symptoms of a rare musculoskeletal condition is significantly more effective than conventional therapies. The findings are published in Lancet.

* This article was originally published here

Museum volunteers discover new species of extinct heron at North Florida fossil site

When the bones of an ancient heron were unearthed at a North Florida fossil site, the find wasn't made by researchers but by two Florida Museum of Natural History volunteers.

* This article was originally published here

HP Enterprise buying supercomputer star Cray

Hewlett Packard Enterprise (HPE) on Friday announced a $1.3 billion deal to buy supercomputer maker Cray, part of a move to expand into data analysis from connected devices .

* This article was originally published here

Dangerous pathogens use this sophisticated machinery to infect hosts

Gastric cancer, Q fever, Legionnaires' disease, whooping cough—though the infectious bacteria that cause these dangerous diseases are each different, they all utilize the same molecular machinery to infect human cells. Bacteria use this machinery, called a Type IV secretion system (T4SS), to inject toxic molecules into cells and also to spread genes for antibiotic resistance to fellow bacteria. Now, researchers at Caltech have revealed the 3-D molecular architecture of the T4SS from the human pathogen Legionella pneumophila with unprecedented details. This could in the future enable the development of precisely targeted antibiotics for the aforementioned diseases.

* This article was originally published here

New computer program can help crack precision medicine

Researchers from ANU have helped develop a new computer program to find out a person's genetic make-up, bringing us a step closer to an era of precision medicine.

* This article was originally published here

Framework improves 'continual learning' for artificial intelligence

Researchers have developed a new framework for deep neural networks that allows artificial intelligence (AI) systems to better learn new tasks while "forgetting" less of what it has learned regarding previous tasks. The researchers have also demonstrated that using the framework to learn a new task can make the AI better at performing previous tasks, a phenomenon called backward transfer.

* This article was originally published here

Identifying the molecular structure of one of Alzheimer's stickier culprits

In a new study published in Proceedings of the National Academy of Sciences, researchers from the University of Colorado Denver and Binghamton University are the first to map the molecular structure and dynamics of an aggressive protein modification that spurs on Alzheimer's disease.

* This article was originally published here

Earthquake in 2009 intensified American Samoa's rising sea levels

The 2009, magnitude-8.1 Samoa earthquake dealt a great deal of damage to the Samoan Islands: Tsunami waves as high as 14 meters (46 feet) wiped out multiple villages, claiming nearly 200 lives and severely damaging water and electrical systems.

* This article was originally published here

China creates app to recognize Pandas

China has developed an app that allows conservationists to identify individual pandas using facial recognition technology, state-run Xinhua news agency reported Friday.

* This article was originally published here

Adult-onset IBD linked to higher mortality

While the onset of inflammatory bowel disease (ulcerative colitis or Crohn's disease) in adulthood is tied to a higher mortality, the actual number of deaths has been falling, a Swedish study from Karolinska Institutet published in the journal Gut reports. Now it is a case of ascertaining which of the newer treatments are the most efficacious, say the researchers.

* This article was originally published here

Exploring people's perception of geometric features, personalities and emotions in videos with virtual humans

Researchers at Pontifical Catholic University of Rio Grande do Sul have recently carried out a study aimed at evaluating people's perceptions of geometric features, personalities and emotions presented in video sequences with virtual humans. Their study, outlined in a paper pre-published on arXiv, merges computer science tools with psychology research practices.

* This article was originally published here

New AI sees like a human, filling in the blanks

Computer scientists at The University of Texas at Austin have taught an artificial intelligence agent how to do something that usually only humans can do—take a few quick glimpses around and infer its whole environment, a skill necessary for the development of effective search-and-rescue robots that one day can improve the effectiveness of dangerous missions. The team, led by professor Kristen Grauman, Ph.D. candidate Santhosh Ramakrishnan and former Ph.D. candidate Dinesh Jayaraman (now at the University of California, Berkeley) published their results today in the journal Science Robotics.

* This article was originally published here

The USDA announces new vision for animal genomics

A new U.S. Department of Agriculture (USDA) blueprint, published today in Frontiers and Genetics, will serve as a guide for research and funding in animal genomics for 2018-2027 that will facilitate genomic solutions to enable producers to meet increasing future demands for animal products by a growing world population.

* This article was originally published here

Research reveals insulin-producing beta cells may change function in diabetes

A revolutionary new study using only materials derived from humans has revealed that insulin-producing beta cells can change their function in diabetes—and that this change may be reversible.

* This article was originally published here

Experimental brain-controlled hearing aid decodes, identifies who you want to hear

Our brains have a remarkable knack for picking out individual voices in a noisy environment, like a crowded coffee shop or a busy city street. This is something that even the most advanced hearing aids struggle to do. But now Columbia engineers are announcing an experimental technology that mimics the brain's natural aptitude for detecting and amplifying any one voice from many. Powered by artificial intelligence, this brain-controlled hearing aid acts as an automatic filter, monitoring wearers' brain waves and boosting the voice they want to focus on.

* This article was originally published here

Could the fabled Orient Express take to the rails again?

It conjures up the atmosphere of rail travel from a bygone golden age, steaming through Europe experiencing top-notch cuisine and the company of fellow passengers who could be writers or spies.

* This article was originally published here

Imagine Apple's App Store with no walled garden

Gregg Spiridellis isn't shy when it comes to his feelings about the Apple iOS App Store.

* This article was originally published here